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2 PACK Brand New - Sealed Volume:1 fl oz SkinMedica's TNS Advanced+ Serum is a skin rejuvenation formula that can significantly improve the appearance of coarse wrinkles, fine lines and sagging skin. With the support of TNS®-MR and Renessensce (RSC) Advanced, this combination promotes skin cell renewal and supports collagen and elastin levels, resulting in a smoother, more radiant and youthful complexion.